A driver sustained life-threatening injuries in a crash at Hindmarsh Valley yesterday afternoon.

Just before 1.15pm on Friday 1 August, police were called to the intersection of Victor Harbor Road near Hindmarsh Tiers Road after reports of a two-car crash involving a Mazda sedan and a Jeep SUV.

The driver of the Mazda, a 66-year-old Aldinga Beach woman, was conveyed to hospital with life threatening injuries.

Her passenger, a 30-year-old woman, was taken to hospital with non-life-threatening injuries.

The Jeep driver, a 61-year-old Encounter Bay man, and passenger, a 62-year-old woman, sustained minor injuries and were taken to hospital.

Investigations into the crash are ongoing.

Anyone who witnessed the crash or has any dashcam footage that may assist the investigation is asked to contact Crime Stoppers on 1800 333 000 or online.